Only Nandrolone Decanoate (Deca durabolin) and Oxandrolone have been studied in HIV related unintentional weight loss. Oxandrolone is a mild oral anabolic but one that can also increase liver enzymes. Nandrolone does not have this issue (it is not a 17 alpha alkylated anabolic), but some men can have increases in hematocrit and blood viscosity (not good for the heart). All anabolic shut down your own body's testosterone production, so it is good to supplement with testosterone to ensure normal sex drive and function. Playing around with anabolic steroids without doing a lot of reading and research is foolish in my opinion. You should be monitored by a physician to follow hematocrit, PSA, blood pressure, estradiol related issues (like breast enlargement), liver enzymes, etc. Men with HIV that are going to use anabolic no matter what at least engage in some harm reduction by reading and informing themselves about these potent hormones that have helped us in the past survive by combating wasting syndrome. A good bodybuilder is a smart bodybuilder. Over eight studies have shown nandrolone to be effective for increasing lean body mass (LBM) and strength in men and women with HIV. A randomized, placebo controlled trial in 38 women conducted by the AIDS Clinical Trials Group (ACTG) reported significant increases in weight and lean body mass after 12 weeks of Nandrolone therapy (100 mg every two weeks). There were no differences between the groups in fat increases or in clinical or laboratory adverse events. Hoarseness, hirsutism, and clitoral enlargement were noted rarely in the treated group. A recent study by Wanke reported that as many as 29 percent of people with HIV in the era of HAART are still losing weight or lean body mass, despite undetectable viral loads.
Nandrolone decanoate is especially attractive because of its benign side effects profile compared to alternative steroids. According to Vergel, unlike oral steroids such as Oxandrin and Anadrol, nandrolone does not impact liver function lab markers at the low doses used in HIV a crucial issue for many people with overtaxed livers from HAART or HCV. One of the FDA approved products to treat HIV-wasting, Megace (megestrol acetate), tends to produce its weight gain due to increases in fat rather than lean body mass -- and adding fat during AIDS wasting has not been shown to improve survival. Megace, a female sex hormone, has also been associated with side effects such as diabetes, blood clots, impotence and the development of female sex characteristics. Another agent approved to treat HIV wasting, Serostim (recombinant human growth hormone), lacks evidence of benefit beyond 12 weeks. FDA-approved appetite stimulants such as Marinol contain the psychoactive ingredient in marijuana (THC), notes Brenda Lein of Project Inform, and "thus is not a preference for many people with HIV who are in recovery." Also, it's theorized that Marinol may simply owe its ability to increase weight to a side effect of the THC high that people get the munchies and tend to eat more.
Winstrol and Equipoise are both not good on the liver since they both are 17 alpha alkylated. Nandrolone is not liver toxic, not 17 alpha alkylated and it has been studied in doses up to 600 mg a week in HIV. Most HIV positive men who need help gaining lean body mass use it at conservative dose of 200 mg Nandrolone plus 200 mg of Testosterone Cypionate every two weeks for 12-16 weeks and most stay on testosterone replacement therapy after stopping the Nandrolone so that you do not lose muscle mass and quality of life.
The FDA and most people did not seem to care even after some of us tried to stop this.You can also gain lean body mass by weight training and consuming a balanced diet. Supplements like creatine, whey protein and others have been shown to help.
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