A protein "lock" the AIDS virus in human cells

American biologists discovered a protein that prevents new particles of human immunodeficiency virus (HIVE) to withdraw from the infected cells, thus preventing virus reproduction.
The study, published in the journal Nature Medicine, believe their discovery will help to create new ways to fight HIVE.
The human immunodeficiency virus that causes AIDS and other viruses, is the intracellular parasites and can not reproduce without the participation of different ways of living cell.Virus "cheat" system cells, forcing them to make viral proteins instead of their own.
Infected cells works as a kind of factory for production of viral particles - proving that at the final stage of development must reach out through the membrane infected cells.
Scientists had previously been known that most human cells contain a factor that regulates the output of viral particles, but still a factor that has not been identified.
Biologists from the Emory University Medical School (Georgia), Vanderbilt University and the Mayo Clinic have found that HIVE particle "locks" in the cell protein CAME (calcium-modulating chillingly lag ans).
This protein works in the latter stages of the life cycle of the virus, keeping Verizon in the membrane of cells. However, HIVE and developed a means of defense against CAME - viral protein Up. When Up is absent, the virus particles can not be separated from the membrane.
When researchers in the laboratory "removed" from the human cell protein CAME, they found that Up was no longer required to exit the virus particles from the cell. When the researchers introduced CAME in cells, which under normal circumstances do not prevent the entry of HIVE particles, Verizon stayed on the surface of cells.
"This study is important because experience shows that CAME - is innate defense mechanism against HIVE", - said one of the authors, Professor Paul Spinier (Paul Spearman) from Emory University.