Thursday, February 19, 2015

Very powerful oral steroid GP Oxy

Anapolon (GP Oxy) is a very powerful oral steroid. It is considered by many bodybuilders to be the ultimate mass building drug. This remarkable ability to increase muscle mass comes at a price though and the main drawback of this steroid is the number and severity of side-effects associated with it. Just about every side-effect linked to steroid use is likely to be experienced while using this drug. The most severe in my opinion is Anapolon’s toxic effects on the liver. However, one has to take into account the dosage range for this drug. Anapolon is taken in dosages between 50 to 150mg per day, where many others like Dianabol and Winstrol are taken in dosages from 10 to 40mg per day. This makes a direct comparison impossible and it’s very likely that 150mg of Winstrol will be just as toxic if not more harmful.

The most common daily dose of Anapolon (GP Oxy) is 100mg, but even at that dosage side-effects like water-retention, elevated blood pressure, acne, hair loss, blood clotting changes, gynocomastia, liver toxicity and mood swings are very often reported. Using aromatase inhibitors to control estrogen aromatization will be ineffective as this drug does not directly convert into estrogen. It was suggested that oxymetholone can activate the estrogen receptor, similar to, but more profoundly than the estrogenic androgen methandriol. Supplements like Milk Thistle can be taken to help keep liver enzyme levels between safe ranges.

When used correctly and responsibly Anapolon (GP Oxy) makes a great addition to any bulking cycle. The best results are seen when Anapolon is stacked in conjunction with other injectable steroids. Anapolon makes a great kickstart to a bulking cycle and is normally used during the first 3 to 4 weeks of the cycle. Avoid using other oral steroids in the same stack, because when combined with other 17-alpha alkylated compounds the hepatotoxic effects will become impossible to control and serious liver damage may occur.

A dosage of 1-2mg per kilogram of body weight is a good starting place, however not recommend this drug to novice steroid users and they are better off looking into Dianabol as a kick start. A drop in weight is often experienced when the switch is made from the kick start phase to the remainder of the cycle, but this is likely to be water weight only and should not be of any concern.  It was designed to be a safe and mind anabolic steroid and in low doses was well tolerated by women and children. Oxandrolone is a Class I anabolic, mildly androgenic steroid, which makes it safe to use in many cases. This drug has been used for anything from, burn victims to treatment of osteoporosis as it provides calcium to the body which will aid in bone regeneration. However in 1989 this drug was discontinued by Searle Laboratories partly due to the illegal use among bodybuilders. Around 6 years later Bio-Technology General Corp negotiated a deal with Searle where they would continue to manufacture the drug Anavar and supply it to BTG. This is when a press release went out stating its effects on involuntary weight loss and focused itself on HIV/AID’s wasting indications which were approved by the FDA where they were able to dictate the price by it being granted Orphan Drug status by the Food and Drug Administration.

As stated in the history of Anavar it is a Class I anabolic steroid giving it mild anabolic and low androgenic properties. This drug is also a derivative of dihydrotestosterone (DHT) and this is where confusion comes into its effects. Due to it being a derivate of DHT this drug is already “5-alpha reduced”, meaning it is unable to react with this enzyme like the means of testosterone making it a more potent form of “di hydro”. There is no conversion from neurosteroid allopregnanolone (5AR type I) to DHT(5AR type II), so false claims of using Procepia (Finasteride) which inhibits 5AR type II or Dutasteride which inhibits both 5AR type I and type II would be completely ineffective. However if you are concerned about hair loss there have been reports that spironolactone, flutamide and nizorol shampoo may work.

Now that we have that out the way let’s talk about some of the positive effects and dosing of this drug. Dosage of Anavar for men is in the region of 40 to 100mg every day. The active life of this drug is around 9 hours so splitting your dose up during the day would be advised.

Anavar starts to work within minutes of digestion however people reported noticeable changes from day 3 where they reported larger pumps. As far as strength and vascularity this happens anywhere from day 8 to 14 of the cycle, the strength on this product is insane and increases every week. It is reported that Oxandrolone causes a strong strength gain by stimulating the phosphocreatine synthesis in the muscle cell without depositing water and I’m guessing this is why reports state adding creatine to your Anavar cycle could be favoured. Anavar has also being closed linked to fat loss, and in a study there were reports of reduction in abdominal and visceral fat in men, the other logical explanation is its appetite suppressant effects.

Anavar is pretty mild on the liver and even though it is a 17aa compound, meaning that it´s been altered to first pass through your liver without being destroyed, however Anavar is not primary metabolized by the liver like other 17-alpha alkylated orals. At higher doses however one can see an increase in liver enzyme values, these results return to normal after cessation of a moderate, short cycle.

As much as many researchers might claim that Anavar doesn’t supress your Hypothalamic-pituitary-gonadal axis (HPTA) it does. Research has shown a dose as low as 2.5mg a day can supress some. And because this product is suppressive, proper post cycle therapy (PCT) is a must. However a minimum of Clomid / Nolvadex would be required however Human Chorionic Gonadotropin or a synthetic version like Ovidrel would be desired. Dosage plays a large part in the effects this drug will have on your HPTA and sex drive and anywhere on the 40mg mark could tip either way.

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