The path of transmission of HIV

There is conflicting data as to whether the development of AIDS as something related to the transmission of the virus through.

Now most scientists have rejected such theories as insolvent. Apparently, the value is not the route of transmission of HIV, and other factors that may be linked to through the transfer. For example, before some were saying that people who are HIV transmission through blood transfusions, the disease progresses rapidly. However, it does not take into account the fact that if a person transfused blood, the more likely he was at an older age, and may suffer other serious illnesses.

Age

Adult progression of HIV infection is faster at an older age. The most noticeable is in people over 40 years. By some estimates the risk of AIDS is increased by 27-55% with each new decade. In one study, conducted among adult hemophiliac, showed that ten years have remained healthy 86% of people infected by the age of 15 years, 72% of people infected between the ages of 15-34 years, 45% of people infected by the age of 34 -54 Years, and only 12% of infected people aged over 55 years. In one Italian study shows that the progression of HIV infection is increasing one and a half times increase in the age of ten years.

The explanation of this phenomenon may be that with increasing age the immune system more difficult to replace CD4 cells with new ones. Perhaps this is due to suppression activities thymus - prostate, generating new cells CD4. Another explanation is that older persons below the level chemokinesis - substances that interfere with HIV to penetrate the cell.

Also, HIV infection can progress rapidly in young children, especially infants. Slower all HIV progression among adolescents.

It is assumed that the young people the best immune response in the transmission of HIV, bringing the viral load has long remained low.

However, according to latest figures, with access to anti-retroviral therapy effect of age on the progression of HIV infection is reduced. However, according to some studies people older than 50 are still difficult to restore the immune status, even when receiving anti-retroviral therapy.