Effect of Dianabol by Geneza Pharmaceuticals

Methandrostenolone is the chemical name for Dianabol. Dianabol (GP Methan) is known as literally the number one most popular and widely used anabolic steroid in existence, with the second most popular being Nandrolone Decanoate (Deca Durabolin), and third being Stanozolol (Winstrol). Dianabol (GP Methan) was also essentially the second anabolic steroid synthetically created, and is the first analogue of Testosterone to ever be developed (discounting Methyltestosterone, which is essentially orally active Testosterone).

The development of Dianabol (GP Methan) for all intents and purposes sparked the beginning of the anabolic steroid development boom, which began in the 1950s. With the Americans at a massive disadvantage, an investigation had been initiated into how the Soviet athletes were vastly superior, and various Soviet Olympic athletes that had defected to America had been studied. Shortly afterwards, it was discovered that these Soviet athletes had been administered supraphysiological amounts of Testosterone via intramuscular injection. It was this administration of Testosterone that was discovered to be a major changing factor in enhancing athletic ability, specifically in the areas of muscular strength.

Dianabol (also known as GP Methan, Dbol, Methandrostenolone, and methandienone) is one of the most popular anabolic steroids and performance enhancing drugs. This steroid is a very anabolic and androgenic drug that provides little progestational activity.

The chemical name of Dianabol (GP Methan) is [17a-methyl-17b-hydroxy-1,4-androstadien-3-one] and its molecular formula is C20H28O2. It has an anabolic-androgenic ratio of 90-210:40-60 and can be detected over a period of six weeks. It has the molecular weight of 300.44 g/mol at the base.

Categorized as a Schedule III drug under the Anabolic Steroid Control Act of 1990, Dianabol (GP Methan) is medically recommended to people suffering with osteoporosis and health complications requiring improved protein synthesis. The fact that 17α-methylation of the steroid helps it easily pass through the liver is one of the biggest reasons behind its popularity. Moreover, this steroid has the ability to minimize SHBG (sex hormone binding globulin), which deactivates steroids to prevent them from further reactions with the body. The drug is also suggested for treating health conditions like chronic adrenocortical insufficiency, thyrotoxicosis, interstitial-pituitary insufficiency, diabetic angiopathies (retinopathy and nephropathy), steroidal diabetes, and pituitary dwarfism. It can even be recommended during radiotherapy for laryngeal tumors.

The steroid has a profound effect on protein metabolism and promotes well being by facilitating positive nitrogen balance. Use of this steroid is also associated with improvement of mood, self-esteem, appetite, and self-confidence enhancements and normalizing effect on all functions of the body to promote physical and mental state and improving sleep patterns. In addition to that, the use of Dbol is linked to enhancements in terms of body calcium and potassium levels and offering assistance in the release of insulin besides transmission of sensor alerts. Dianabol is also admired by sportsmen as it its use for a period of six to eight weeks is related with glycogenolysis, nitrogen storage, protein synthesis, muscle mass, muscle function, and body strength gains that are nearly permanent. Dbol is commonly used by sportsmen to kick-start mass and strength gains at the start of a long bulking cycle. Since Dianabol (GP Methan) has a short active life, multiple doses of it are required to be taken throughout the day.

The recommended dose of Dbol for men is 25-50 mg per day when taken orally and 50-150 mg per week when taken in an injectable form. The anabolic compound is generally stacked with testosterone enanthate, Nandrolone, Anadrol, Proviron, Testosterone Propionate, Trenbolone acetate, and testosterone cypionate and post cycle therapy with antiestrogens such as Clomid and Nolvadex is highly recommended to restore production of naturally-occurring testosterone and reduce or eliminate estrogenic side effects.

This anabolic steroid is not recommended to girls and women, especially those who may get pregnant while using the steroid or already pregnant or lactating. Its use is also not recommended to children or those struggling with hypertension, high blood pressure, and prostate or breast cancer. Dbol should also not be used by people having an existing allergy to its ingredients. Use of Dianabol is not recommended to those suffering from health problems like testicular atrophy, testicular cancer, prostate cancer, breast cancer, liver damage, kidney damage, stroke, high blood pressure and respiratory problems.

Since Dbol can convert to estradiol via aromatase, estrogenic side effects may be a concern for users of this steroid. Some of the most common side effects of Dianabol include oily skin, acne, gynecomastia, water retention, and high blood pressure. In rare cases, nose bleeding may be a cause of concern while using Methandrostenolone. In order to avoid these side effects of Dbol, it is best to use an estrogen blocker such as Nolvadex or an aromatase inhibitor such as Arimidex. Being a 17-alpha-alkylated compound, Dbol (GP Methan) use can cause elevated liver values and therefore users of this anabolic steroid are advised to monitor liver function at regular intervals. Since liver toxicity may become a problem for some Dbol users, it is best to have ready supplies of Tyler Liver Detox or Milk Thistle. Moreover, users of the steroid should consume 7-9 glasses of water and take other liquids such as fresh juices at regular intervals or if the need arises. Dianabol use may cause side effects like increased aggression, male pattern baldness, clitoral hypertrophy, oily skin bouts, and insomnia and indiscriminate use of this steroid may lead to difficulty when urinating, edema (swelling), fever, or pain in the lower back (particularly in the kidney areas) and even high blood pressure and damage to kidneys. At no point of time, this anabolic steroid should be used in absence or contravention of medical advice. Moreover, use of Dianabol should always be made for a legal purpose and as per medical directions. In case a dose of the steroid is missed, for any reason, the same should be ignored and the next dose should be taken as scheduled.

Benefits of GP Methan by Geneza Pharmaceuticals

GP Methan by Geneza Pharmaceuticals was more or less the second anabolic steroid ever produced. The first, as we all know was Testosterone, which was produced in the early 1900s and experimented with by Nazis in WW2, in an attempt to produce a better soldier. Enough with the history lesson, lets get into what this GP Methan is and what it does. Well, first off, its usually found in pill form, though it can be found as an injectable also (Under the Trade name: Reforvit-B, which is 25mgs of methandrostenolone mixed with B-vitamins). GP Methan is a 17aa steroid, which means it has been altered at the 17th Carbon position, to survive its first pass through your liver, and make it into your blood stream. GP Methan will raise your blood pressure and is also hepatoxic (Liver-Toxic), so be careful with it. Lets examine this particular study a bit further, though:

GP Methan this study, done in the early 80s, a very high dose of Dianabol (100mgs/day for 6 weeks) decreased plasma testosterone to about 40% of its normal value, plasma GH went up about a third, LH dropped to about 80% of its original value, and FSH went down about a third also (these are all approximate numbers, for the sake of brevity, but you get the idea). Body fat did not go up significantly and fat free mass went up anywhere between 2-7kgs (3.3kgs average gain). The researchers concluded that GP Methan increases Fat Free Mass as well as increasing strength and performance.

Side effects:
As with many other 17aa steroids, GP Methan is also a very weak binder to the androgen receptor, so most of its effects are thought to be non-receptor mediated, and are attributable to other mechanisms (i.e. protein synthesis as indicated by the production of muscle tissue with very high levels of nitrogen, etc. which was indicated in the 100mg/day study). This also means GP Methan only has a modest aromatase activity.

In order to kick start a Dianabol cycle, usually what you do is incorporate a fast acting oral like GP Methan (or anadrol) and combine it with long acting injectables (such as Deca or Equipoise with some Testosterone). The reasoning here is that the oral will give almost immediate results, while the injectable takes time to produce results. The end result is that you start seeing results within the first week of your cycle and continue up until the end with the injectables. This entails taking anywhere from 25-50mgs of dbol (although as little as 20mgs or as much as 100mgs have been reported) for 3-6 weeks at the start of a cycle (average time for a "Kick Start" is 4 weeks, though), and then ceasing their use as the injectables start to produce results.

In order to successfully bridge between cycles (and this means using a low dose of anabolic steroids, in this case dbol), you need to recover your natural hormonal levels to pre-cycle levels or to within acceptable parameters, and then you start your next cycle. The idea here is that you wont lose any gains, but rather a low dose of an anabolic steroids will help you maintain them. Typically, you'd use around 10mgs/day of dbol and combine it with an aggressive Post-Cycle Therapy (PCT) course of Nolvadex (and/or Clomid) and HCG. This would give you full androgen replacement from the GP Methan and a shot at recovering your natural hormonal levels via the other stuff you are taking. Remember, the 100mg/day dose of dbol in the study we looked at earlier did not suppress Test, LH, or FSH to a degree that would make recovery impossible and certainly not with 1/10th that dose in conjunction with an aggressive PCT.